Immunology defend us from foreign macro molecules or invading micro organisms. Invaders are viruses, bacteria, protozoa & larger parasites. Specific immune system includes that we see the production of antibodies, soluble proteins which bind foreign antigens & cell-mediated responses but specific cells recognize foreign pathogens and destroy them. But in viruses or tumors, this response is also vital to recognise and destroy of virally infected or tumorigenic cells. We develop immune responses against our own proteins & other molecules in autoimmunity against our own aberrant cells in tumor immunity. Ocular inflammatory diseases are a group ophthalmic conditions that are related to infectious, autoimmune and masquerade diseases.