Pediatric Infectious Disease & Microbiome
Many of these pediatric diseases are connected with the altered states of the microbiome. These microbiotas of the allergic and nonallergic infants are much different. The Earlier colonization with the bacteria are Bacteroides fragilis & Clostridium coccoides are then associated with the increased risk factor for asthma in children Changes the microbiota are also linked with the skin diseases including the psoriasis, atopic dermatitis and acne. Hygiene hypothesis proposes that improved hygiene leads to decreased exposure to infectious agents in early life that could cause increase in immune dysregulation and atopic diseases.